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Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Idetrexed
go.drugbank.com/drugs/DB21469InvestigationalThe usage of the INN stem '-trexed' in the name indicates that Idetrexed is a antineoplastic; thymidilate synthetase inhibitor. … Idetrexed is under investigation in clinical trial NCT02360345 (Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly). Idetrexed has a monoisotopic molecular weight of 647.22 Da.
Hydronidone
go.drugbank.com/drugs/DB06299InvestigationalHydronidone has antifibrotic activity.
Synonyms: N-(4-Hydroxyphenyl)-5-methyl-2-pyridoneAprinocarsen
go.drugbank.com/drugs/DB06451InvestigationalAprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha.
MLN576
go.drugbank.com/drugs/DB06517ExperimentalXR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.