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Beloranib
go.drugbank.com/drugs/DB12671InvestigationalBeloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
Gandotinib
go.drugbank.com/drugs/DB13040InvestigationalGandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Synonyms: 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL-3-YL)-8-(4-MORPHOLINYLMETHYL)-Methylcantharidimide
go.drugbank.com/drugs/DB18959InvestigationalMethylcantharidimide is under investigation in clinical trial NCT03996681 (TACE Combined With Methylcantharidimide Tablets in the Treatment of Large and Unresectable Hepatocellular Carcinoma).
Synonyms: N-methylcantharidimideCV-8102
go.drugbank.com/drugs/DB19184InvestigationalCV-8102 is under investigation in clinical trial NCT03203005 (IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients).
Cesium Cs-131
go.drugbank.com/drugs/DB19250InvestigationalCesium Cs-131 is under investigation in clinical trial NCT04340258 (Trial Combining Pembrolizumab and Cesium 131 Brachytherapy With Salvage Surgery in HNSCC).
Firazorexton
go.drugbank.com/drugs/DB19440InvestigationalFirazorexton is under investigation in clinical trial NCT04096560 (A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy).
Synonyms: N-((2s,3s)-1-(2-hydroxy-2-methylpropanoyl)-2-((2,3',5'-trifluorobiphenyl-3-yl)methyl)pyrrolidin-3-yl)methanesulfonamide, Methanesulfonamide, n-((2s,3s)-1-(2-hydroxy-2-methyl-1-oxopropyl)-2-((2,3',5'-trifluoro(1,1'-biphenyl)-3-yl)methyl)-3-pyrrolidinyl)-MLN2704
go.drugbank.com/drugs/DB06513InvestigationalA Phase 1/2 trial (NCT00070837) evaluated the safety, dosage, and pharmacokinetics of MLN2704 in patients with metastatic androgen-independent prostate cancer.
MBX-2044
go.drugbank.com/drugs/DB05598InvestigationalMBX-2044 was under investigation in clinical trial NCT00422487 (Safety and Tolerability Study of MBX-2044 in Patients With Type 2 Diabetes).
Pevonedistat
go.drugbank.com/drugs/DB11759InvestigationalPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Oxfendazole
go.drugbank.com/drugs/DB11446InvestigationalVet approvedThis benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.