Methylcantharidimide

DB18959InvestigationalSmall molecule

Methylcantharidimide is under investigation in clinical trial NCT03996681 (TACE Combined With Methylcantharidimide Tablets in the Treatment of Large and Unresectable Hepatocellular Carcinoma).

Chemical structure of Methylcantharidimide
Formula / weight
C11H15NO3 · 209.245 g/mol (avg)
Also known as
4,7-EPOXY-1H-ISOINDOLE-1,3(2H)-DIONE, HEXAHYDRO-2,3A,7A-TRIMETHYL-, (3AR,4S,7R,7AS)-REL- · N-methylcantharidimide

Resolves to

Structure
InChIKeyWUQNOBSCYAIJIH-FIPCFZRWSA-NSMILESCN1C(=O)[C@@]2(C)[C@@H]3CC[C@@H](O3)[C@@]2(C)C1=O

What you can answer from here — as of April 02, 2025

1Clinical trialPhase, status and sponsor resolved per trial
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Which companies are running trials of Methylcantharidimide, in which indications and phases, and which of those programs are still active?

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