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Cholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnCholecystokinin ( also known as _CCK or CCK-PZ_) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. … Recent studies have suggested that cholecystokinin also plays a major role in inducing drug tolerance to opioids such as morphine and heroin, and is partially implicated in experiences of pain hypersensitivity
Categories: Tests for Pancreatic FunctionHeparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalUnfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. … Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
Categories: Heparins or Heparinoids for Topical UseProducts: BRAUN HEPARINISED SALINE 10IU/ML SOLUTION FOR INJECTION, HEPARIN AL GEL 30000Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approvedLotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. … [A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551]
Erythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalvarious clinical conditions, such as chronic renal failure, antiviral drug therapy, chemotherapy, or a high risk for perioperative blood loss from surgical procedures [FDA Label]. … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of patients with anemia associated with
Products: EPO STADA 2000IU/0.6ml Solution for Injection in a Pre-filled Syringe, EPO STADA 4000IU/0.4ml Solution for Injection in a Pre-filled SyringeReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalIL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. … It is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines. Reslizumab is marketed as Cinqaero in Europe.
Categories: Drugs for Obstructive Airway DiseasesFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Categories: Antihypertensive Agents Indicated for HypertensionProducts: FOSINOPRIL NaPeramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalDue to the poor oral bioavailability, the oral formulation of the drug was previously abandoned by Johnson and Johnson Company. … The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalmutations, or ALK, ROS1 or RET genomic tumour aberrations. … [L32868] Sugemalimab was under investigation in the clinical trial NCT03802591 (A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-esophageal Junction Adenocarcinoma).
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsFormaldehyde
go.drugbank.com/drugs/DB03843ApprovedVet approvedA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. … In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative.
Mixtures: British Army Foot PwrCategories: Compounds used in a research, industrial, or household settingHydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications. … [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.
Categories: Antihypertensive Agents Indicated for HypertensionProducts: APRESOLINE FOR INJECTION 20 mg/ampoule