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Tasosartan
go.drugbank.com/drugs/DB01349ExperimentalIt is used to treat patients with essential hypertension. … Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAprobarbital
go.drugbank.com/drugs/DB01352ExperimentalIllicitAprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. … Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects.
Synonyms: 5-(1-methylethyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-isopropylbarbituric acidCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersLithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnIt is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Ephedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalEphedra is an alkaloid chemical compound traditionally obtained from the plant _Ephedra sinica_. … The drug is still sold in Canada in OTC formulations for respiratory conditions associated with bronchial asthma.
Mixtures: Miller's Formula No. 1Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Adrenergic alpha-2 Receptor AgonistsAluminium
go.drugbank.com/drugs/DB01370ApprovedInvestigationalWithdrawnA metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
Aluminium monostearate
go.drugbank.com/drugs/DB01375ExperimentalAluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. … Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics.
Glymidine
go.drugbank.com/drugs/DB01382ApprovedIt is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. … Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin.
Mibefradil
go.drugbank.com/drugs/DB01388ApprovedWithdrawnMibefradil was withdrawn from the market in 1998 because of potentially harmful interactions with other drugs.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTemafloxacin
go.drugbank.com/drugs/DB01405ApprovedWithdrawnTemafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. … It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three
Categories: 4-Quinolones, Cytochrome P-450 SubstratesClenbuterol
go.drugbank.com/drugs/DB01407ApprovedInvestigationalVet approvedA substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Synonyms: 1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol, 4-amino-α-((tert-butylamino)methyl)-3,5-dichlorobenzyl alcoholMixtures: BRONCOCHEM® F JARABE ADULTOS, BRONCOCHEM® F JARABE ADULTOS