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Y-27632
go.drugbank.com/drugs/DB08756InvestigationalY-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Synonyms: (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamideIdazoxan
go.drugbank.com/drugs/DB12551InvestigationalIdazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
Icaritin
go.drugbank.com/drugs/DB12672InvestigationalIcaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
Felcisetrag
go.drugbank.com/drugs/DB12725InvestigationalFelcisetrag (TD-8954) has been used in trials studying the treatment of Enteral Feeding Intolerance and Gastrointestinal Motility Disorder.
Perfosfamide
go.drugbank.com/drugs/DB12727InvestigationalPerfosfamide has been used in trials studying the treatment of Lymphoma, Neuroblastoma, and Multiple Myeloma and Plasma Cell Neoplasm.
Delparantag
go.drugbank.com/drugs/DB12955InvestigationalDelparantag has been used in trials studying the treatment of Angioplasty, Coronary Artery Disease (CAD), and Percutaneous Coronary Intervention.
PCI-27483
go.drugbank.com/drugs/DB13000InvestigationalPCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.
Tocladesine
go.drugbank.com/drugs/DB13046InvestigationalTocladesine has been used in trials studying the treatment of Colorectal Cancer and Multiple Myeloma and Plasma Cell Neoplasm.
PX-102
go.drugbank.com/drugs/DB15416InvestigationalPX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study With Px-102).
PF-05105679
go.drugbank.com/drugs/DB15450InvestigationalPF-05105679 is under investigation in clinical trial NCT01393652 (Single Dose, Dose Escalation Healthy Volunteers Study Of PF-05105679).