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DNA damage-inducible transcript 4 protein
go.drugbank.com/bio_entities/BE0003445TargetHumansRegulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 comple...
Polypeptides: DNA damage-inducible transcript 4 proteinFunction: 14-3-3 protein bindingTrafficking protein particle complex subunit 4
go.drugbank.com/bio_entities/BE0004278TargetHumansCore component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable). Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy (PubMed:31794024)...
Polypeptides: Trafficking protein particle complex subunit 4Serine/arginine-rich splicing factor 4
go.drugbank.com/bio_entities/BE0009120TargetHumansPlays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10
Polypeptides: Serine/arginine-rich splicing factor 4Synonyms: Splicing factor, arginine/serine-rich 4Neurogenic locus notch homolog protein 4
go.drugbank.com/bio_entities/BE0010483TargetHumansFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator comple...
Polypeptides: Neurogenic locus notch homolog protein 4Synonyms: Notch 4Solute carrier family 4 member 11
go.drugbank.com/bio_entities/BE0017156TransporterHumansIn the presence of borate B(OH)4(-), acts as a voltage-dependent electrogenic Na(+)-coupled B(OH)4(-) cotransporter controlling boron homeostasis (PubMed:15525507). … In the absence of B(OH)4(-), acts as a Na(+)-coupled OH(-) or H(+) permeable channel with implications in cellular redox balance (PubMed:15525507, PubMed:28642546).
Polypeptides: Solute carrier family 4 member 11Ciclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Mixtures: LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,120 KAPSÜL, LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇIEREN KAPSÜL,60 KAPSÜLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCardiolipin Biosynthesis CL(20:3(8Z,11Z,14Z)/18:2(9Z,12Z)/18:2(9Z,12Z)/18:2(9Z,12Z))
smpdb.ca/view/SMP0029573MetabolicThird, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).
Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphateEnzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrialCardiolipin Biosynthesis CL(18:2(9Z,12Z)/18:2(9Z,12Z)/18:2(9Z,12Z)/20:3(11Z,14Z,17Z))
smpdb.ca/view/SMP0217689MetabolicThird, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).
Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphateEnzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrialCardiolipin Biosynthesis CL(18:2(9Z,12Z)/18:2(9Z,12Z)/20:2(11Z,14Z)/20:3(11Z,14Z,17Z))
smpdb.ca/view/SMP0217713MetabolicThird, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).
Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphateEnzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrialCardiolipin Biosynthesis CL(18:2(9Z,12Z)/18:2(9Z,12Z)/20:3(11Z,14Z,17Z)/18:2(9Z,12Z))
smpdb.ca/view/SMP0217724MetabolicThird, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).
Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphateEnzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial