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Displaying results 9181 - 9190 of 10000 in total
  1. Drug

    Resiniferatoxin

    go.drugbank.com/drugs/DB06515
    Investigational

    Resiniferatoxin (RTX) is a naturally occurring, ultrapotent capsaicin analog that activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission

  2. Drug

    MLN576

    go.drugbank.com/drugs/DB06517
    Experimental

    XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]

  3. Drug

    Mesmulogene ancovacivec

    go.drugbank.com/drugs/DB06584
    Investigational

    A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities … Vaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen,

  4. Drug

    Pegsunercept

    go.drugbank.com/drugs/DB06611
    Investigational

    Pegsunercept is used for treating rheumatoid arthritis. Phase II clinical trials were completed in January 2010.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    IMA901

    go.drugbank.com/drugs/DB06628
    Investigational

    IMA901 is a vaccine consists of tumor-associated peptides (TUMAPs).

  6. Drug

    Bevasiranib

    go.drugbank.com/drugs/DB06642
    Investigational

    Bevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A).

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    GMK

    go.drugbank.com/drugs/DB06661
    Experimental

    GMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma

  8. Drug

    Asoprisnil

    go.drugbank.com/drugs/DB06680
    Investigational

    Asoprisnil (J867) is a selective progesterone receptor modulator. It can be used to treat progesterone sensitive myomata.

  9. Drug

    Bufuralol

    go.drugbank.com/drugs/DB06726
    Experimental

    Bufuralol is a new, non-selective -adrenoceptor blocking agent.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  10. Drug

    9-aminocamptothecin

    go.drugbank.com/drugs/DB12515
    Investigational

    Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates