Search
Citric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedA key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Mixtures: Sal de Uvas Picot, Sal de Uvas PicotCategories: Compounds used in a research, industrial, or household settingEstetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigational[L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. … The combination of drospirenone and estetrol offers a new choice with a favourable safety profile for women seeking contraceptive therapy.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAME-527
go.drugbank.com/drugs/DB05879ExperimentalAME-527 is a humanized monoclonal antibody that recognizes human TNF-alpha (hTNF-alpha) with high affinity and specificity. … AME-527 was generated by protein engineering and identified from a library of antibody variants based on its improved binding properties.
Esketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigational[L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive disorder who have not experienced an improvement in symptoms despite treatment with various medications … The intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to
Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone, L-ketamineMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalMepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline. … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote fibrosis, all of which contribute to the multifactorial symptomatology of hypereosinophilic diseases
Categories: Interleukin-5 AntagonistProducts: NUCALA® 100MG/ML SOLUCION INYECTABLE, Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (1 adet)Dequalinium
go.drugbank.com/drugs/DB04209Approved[A249255] It is a quaternary ammonium compound,[L42190] as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. … Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties.
Mixtures: DEQ LOZENGE, DEQ LOZENGECategories: Heterocyclic Compounds, 2-RingGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalThe main effect of SUs is thought to be effective when residual pancreatic β-cells are present,[A177715] as they work by stimulating the release of insulin from the pancreatic beta cells and they are also … 2 diabetes mellitus.
Mixtures: METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADA, METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesDiphenidol
go.drugbank.com/drugs/DB01231ApprovedWithdrawnDiphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Diphenyl(3-(1-piperidyl)propyl)carbinol, alpha,alpha-Diphenyl-1-piperidinebutanolMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalAs a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a
Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol AL-Glutamine
go.drugbank.com/drugs/DB00130ApprovedInvestigationalNutraceuticalIt is the principal carrier of nitrogen in the body and is an important energy source for many cells. … A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia.
Synonyms: L-Glutaminsäure-5-amid, L-glutamic acid γ-amideInternational brands: L-Glutamine Power