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Bempedoic acid
go.drugbank.com/drugs/DB11936ApprovedInvestigationalHigh levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. … [L12180] Bempedoic acid is first-in-class adenosine triphosphate-citrate lyase (ACL) inhibitor used once a day for reducing LDL cholesterol levels in statin-refractory patients.
Kynurenic Acid
go.drugbank.com/drugs/DB11937InvestigationalKynurenic Acid is under investigation in clinical trial NCT02340325 (FS2 Safety and Tolerability Study in Healthy Volunteers).
Categories: Heterocyclic Compounds, 2-RingIngavirin
go.drugbank.com/drugs/DB11944InvestigationalIngavirin has been used in trials studying the treatment of Influenza and Common Cold.
Categories: Heterocyclic Compounds, 1-RingMK-7145
go.drugbank.com/drugs/DB11968InvestigationalMK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingApabetalone
go.drugbank.com/drugs/DB12000InvestigationalApabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease.
Categories: Heterocyclic Compounds, 2-RingAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VERZENIO® 100 MG, VERZENIO® 150 MGGW-406381
go.drugbank.com/drugs/DB12009InvestigationalGW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.
Categories: Heterocyclic Compounds, 1-RingPF-04457845
go.drugbank.com/drugs/DB12012InvestigationalPF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence.
Categories: Heterocyclic Compounds, 1-RingMapracorat
go.drugbank.com/drugs/DB12041InvestigationalMapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis.
Categories: Heterocyclic Compounds, 2-RingMK-0893
go.drugbank.com/drugs/DB12044InvestigationalMK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-Ring