MK-7145

DB11968InvestigationalSmall molecule

MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.

Mechanism: Pharmacologically active on ATP-sensitive inward rectifier potassium channel 1
Curator reviewed
Formula / weight: C₂₆H₃₀N₂O₆ · 466.534 g/mol (avg)
Code names: MK-7145

Resolves to

Compound

Structure

InChIKeyOCKGFTQIICXDQW-ZEQRLZLVSA-NSMILESCC1=C2COC(=O)C2=CC=C1[C@@H](O)CN1CCN(C[C@H](O)C2=C(C)C3=C(C=C2)C(=O)OC3)CC1

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with MK-7145, and which of those have an active Phase 3 trial?

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