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Displaying results 9281 - 9290 of 10000 in total
  1. Drug

    Verubecestat

    go.drugbank.com/drugs/DB12285
    Investigational

    In the study, administration of Verubecestat at doses of 12, 40 and 60 mg resulted in a dose-dependent and sustained reduction in the levels of Ab40, a measure of BACE1 activity, in CSF from baseline of … Verubecestat is Merck’s investigational oral β-site amyloid precursor protein cleaving enzyme (BACE1 or β secretase) inhibitor.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Simendan

    go.drugbank.com/drugs/DB12286
    Experimental

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  3. Drug

    Piromelatine

    go.drugbank.com/drugs/DB12288
    Investigational

    Piromelatine has been used in trials studying the treatment of Alzheimer's Disease.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    Puerarin

    go.drugbank.com/drugs/DB12290
    Investigational

    Puerarin has been investigated for the treatment of Alcohol Abuse.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  5. Drug

    Nefopam

    go.drugbank.com/drugs/DB12293
    ApprovedInvestigationalWithdrawn

    Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.

    Categories: Heterocyclic Compounds, 1-RingProducts: KATAMOX® SOLUCIÓN INYECTABLE
  6. Drug

    Evodenoson

    go.drugbank.com/drugs/DB12295
    Investigational

    Evodenoson has been used in trials studying the treatment of Open-angle Glaucoma and Ocular Hypertension.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    GLPG-0187

    go.drugbank.com/drugs/DB12297
    Investigational

    GLPG0187 has been used in trials studying the treatment of Solid Tumors.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Cipargamin

    go.drugbank.com/drugs/DB12306
    Investigational

    Cipargamin has been used in trials studying the treatment of Malaria, Cure Rate, and Plasmodium Falciparum Malaria.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Foretinib

    go.drugbank.com/drugs/DB12307
    Investigational

    Foretinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally available small molecule compound desig...

    Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Idasanutlin

    go.drugbank.com/drugs/DB12325
    Investigational

    Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.

    Synonyms: BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL)AMINO)-3-METHOXY-Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-mdm2, antagonists & inhibitors