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Ethynodiol diacetate
go.drugbank.com/drugs/DB00823ApprovedAlthough etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug
Categories: Sex Hormones and Modulators of the Genital SystemVaricella zoster vaccine (recombinant)
go.drugbank.com/drugs/DB13924ApprovedInvestigationalShingrix also contains an adjuvant system, AS01B, which is intended to enhance the immunological response to the vaccine leading to longer lasting and greater immunogenicity to the herpes zoster virus … Immune exposure to gE protein stimulates the development of anti-gE antibodies, and therefore adaptive immunity to VZV.
Synonyms: gE recombinant Varicella zoster virus (VZV) glycoprotein E, gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein EMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. … [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207]
Mixtures: VOKANAMET TM TABLETAS RECUBIERTAS 50 / 1000MG, PIOGLITAZONE E METFORMINA EGProducts: GLUCIBETINA-T, Metformin Hydrochloride E/rGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigational[A182993] The drug was approved by the FDA in 2001 for the treatment of mild to moderate dementia of the Alzheimer's type. … Galantamine works to block the enzyme responsible for the breakdown of acetylcholine in the synaptic cleft, thereby enhancing cholinergic neuron function and signalling.
Products: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL ® ER CAPSULAS DE 16 MGPergolide
go.drugbank.com/drugs/DB01186ApprovedVet approvedWithdrawnThe drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. … It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome. It was later found that pergolide increased the risk of cardiac valvulopathy.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGepotidacin
go.drugbank.com/drugs/DB12134ApprovedInvestigational[L52680,L52685] In December later the same year, the FDA approved another indication for gepotidacin for the treatment of uncomplicated urogenital gonorrhea. [L54803] … [A273755] By inhibiting two distinct bacterial enzymes, a lower potential for the development of resistance to gepotidacin is expected.
Nabilone
go.drugbank.com/drugs/DB00486ApprovedInvestigationalNabilone is a racemate consisting of the (S,S) and the (R,R) isomers. … Nabilone is approved by the FDA for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments [FDA
Allopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalAllopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705 … It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677].
Atoltivimab
go.drugbank.com/drugs/DB15898ApprovedInvestigational[A222078] The chief surface target of EBOV particles is the GP<sub>1,2</sub> glycoprotein, which also appears on the surface of EBOV-infected cells, offering opportunities for both neutralizing and cytotoxic … [A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid development, low toxicity, and high
Ceftizoxime
go.drugbank.com/drugs/DB01332ApprovedWithdrawnIt has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. … The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
Products: E-ZOX