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Cabozantinib
go.drugbank.com/drugs/DB08875ApprovedInvestigational[L15123] In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal cell carcinoma, and this same formulation gained additional approval in both the US and Canada in 2019 … Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsProducts: CABOMETYX FILM COATED TABLET 20MG, CABOMETYX 20mg film-coated tabletsPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalAs the binding of pantoprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, pantoprazole's duration of antisecretory effect persists … Pantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme
Categories: Alimentary Tract and Metabolism, pantoprazole, amoxicillin and clarithromycinProducts: PANTOPRAZOL HEXAL K 20MG, PANTOPRAZOL HEXAL K 40MGgamma-Aminobutyric acid
go.drugbank.com/drugs/DB02530ApprovedInvestigationalThe most common inhibitory neurotransmitter in the central nervous system.
Mixtures: Medi-doze Sleep Aid, Medi-doze Rx Sleep AidCategories: Amino Acids, Peptides, and ProteinsTibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalIn June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S. … Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemProducts: LIVIAL TABLET 2.5MG, TIBOLEEN 2.5MG TABLETSGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approvedGentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by
Mixtures: Garasone Ophthalmic and Otic SolutionCategories: Ophthalmological and Otological PreparationsXylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnXylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood. … Nevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes.
Products: Xylo-tol Pwr 25gm/pckClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approved[A190657] Clindamycin is derived from, and has largely replaced, [lincomycin], a naturally occurring lincosamide and the eponymous member of this antibiotic class, due to its improved properties over … The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621]
Mixtures: CLINDAMICINA / CLOTRIMAZOL 100MG/200MG, Clindamycin and Benzoyl PeroxideCategories: Genito Urinary System and Sex Hormones, Macrolides, Lincosamides and StreptograminsFibrinogen human
go.drugbank.com/drugs/DB09222ApprovedInvestigationalIt is a soluble plasma glycoprotein with a molecular weight of about 340 kDa and is a physiological substrate for three enzymes: plasmin, factor XIIIa, and thrombin. … It is indicated for the treatment of acute bleeding episodes in patients with both acquired and congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.[L41065]
Mixtures: Tisseel Lyo - Pulver und Lösungsmittel für einen GewebekleberCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsTepotinib
go.drugbank.com/drugs/DB15133ApprovedInvestigationalTepotinib was first approved in Japan in March 2020 for the treatment of non-small cell lung cancers (NSCLC) with _MET_ alterations, and was subsequently granted accelerated approval by the US FDA in February … overexpressed and/or mutated.
Categories: Antineoplastic and Immunomodulating AgentsProducts: TEPMETKO FILM-COATED TABLET 225MGMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns … [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995.
Categories: Mycophenolic Acid and ProdrugsProducts: MYFENAX 250MG, CELLCEPT 250MG