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Promazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, N-(3-Dimethylaminopropyl)phenothiazineChenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalChenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. … It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPeanut oil
go.drugbank.com/drugs/DB13964ApprovedWithdrawnPeanut oil is derived from _Arachis hypogaea_ which can be found in South America, Mexico, and Centro America. … [A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in drug products.
Products: Oilatum Soap - 2%Debrisoquine
go.drugbank.com/drugs/DB04840ApprovedAn adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. … Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPixantrone
go.drugbank.com/drugs/DB06193ApprovedWithdrawnPixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. … It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox
Synonyms: 6,9-bis((2-aminoethyl)amino)benzo(g)isoquinoline-5,10-dioneCategories: Heterocyclic Compounds, 2-RingPegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigational[A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis further upstream of C5. … [A235000,A235005] Pegcetacoplan is a pegylated C3 inhibitor that can disrupt the processes leading to both forms of hemolysis that threaten patients with PNH.
Products: EMPAVELI® 54 MG/ML SOLUCIÓN INYECTABLETioguanine
go.drugbank.com/drugs/DB00352ApprovedInvestigationalAn antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-Aminopurin-6-thiol, 2-Amino-6-purinethiolAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnNevertheless, the drug was formally withdrawn worldwide in May of 2008 after studies confirmed that its use enhanced the risk of complications or death. … Aprotinin is a protein-based drug that is also known as bovine pancreatic trypsin inhibitor (BPTI).
Mixtures: SAN. VE TİC. LTD., ŞTİ.EL LYO 1 ML TROMBIN ÇÖZELTİSİ VE 1 ML FIBRINOJEN ÇÖZELTİSİ ICEREN IKI BILESENLI FIBRIN YAPISTIRICI, SET 1 (2 İĞNE+2 ENJEKTÖR) VE SET 2 (2 İĞNE +2 ENJEKTÖR+1 ENJEKTÖR KLİPSİ+2 BİRLEŞTİRME PARÇASI+ 4Naloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors. … [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use.
Synonyms: 1-N-Allyl-14-hydroxynordihydromorphinone, 17-allyl-3,14-dihydroxy-4,5α-epoxymorphinan-6-oneMixtures: TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADA, TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADASerine repeat antigen 5
go.drugbank.com/bio_entities/BE0009196TargetPlasmodium falciparumPolypeptides: Serine repeat antigen 5