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EB05
go.drugbank.com/drugs/DB16477InvestigationalEB05, in combination with standard of care (SOC), is being investigated in clinical trial NCT04401475 to evaluate its safety and efficacy in adult hospitalized patients with COVID-19 and ARDS.
Trevogrumab
go.drugbank.com/drugs/DB15159InvestigationalTrevogrumab is under investigation in clinical trial NCT02943239 (Study of Safety, Tolerability, and Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women
Uproleselan
go.drugbank.com/drugs/DB14829Investigationalin AML). … Uproleselan is a novel, specific E-Selectin antagonist under investigation in clinical trial NCT02306291 (Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy
QR-313
go.drugbank.com/drugs/DB17867InvestigationalQR-313 is an antisense oligonucleotide targeting exon 73. It is being investigated for the treatment of dystrophic epidermolysis bullosa.[A259867]
NBQ72S
go.drugbank.com/drugs/DB26052InvestigationalNBQ72S is a small molecule drug. NBQ72S is under investigation in clinical trial NCT06810804 (A Phase IIa Study to Evaluate NBQ72S).
Picoplatin
go.drugbank.com/drugs/DB04874InvestigationalPicoplatin is a cytotoxic platinum compound in clinical development for the treatment of patients with solid tumors. … It causes apoptosis (cell death) by binding to DNA and interfering with DNA replication and transcription.
Peginterferon lambda-1a
go.drugbank.com/drugs/DB14767InvestigationalPeginterferon lambda-1a is under investigation in clinical trial NCT01754974 (Safety and Efficacy Study of Peginterferon Lambda-1a vs. … Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C).
Galegenimab
go.drugbank.com/drugs/DB18860InvestigationalGalegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to
Lomvastomig
go.drugbank.com/drugs/DB19060InvestigationalLomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous
OBI-3424
go.drugbank.com/drugs/DB16057InvestigationalOBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL
Synonyms: 3-(5-((1R)-1-(Bis(aziridin-1-yl(phosphoryloxy)ethyl)-2-nitrophenoxy)-N,N-dimethylbenzamide, 3-[5-[(1R)-1-[bis(aziridin-1-yl(phosphoryloxy]ethyl]-2-nitrophenoxy]-N,N-dimethylbenzamide