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Baloxavir
go.drugbank.com/drugs/DB15675InvestigationalBaloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingABT-288
go.drugbank.com/drugs/DB15192InvestigationalABT-288 is under investigation in clinical trial NCT01018875 (Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease).
Categories: Heterocyclic Compounds, 1-RingNumidargistat
go.drugbank.com/drugs/DB15286InvestigationalCB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).
Categories: Heterocyclic Compounds, 1-RingRidinilazole
go.drugbank.com/drugs/DB15308InvestigationalRidinilazole is under investigation in clinical trial NCT02092935 (A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPovorcitinib
go.drugbank.com/drugs/DB18855InvestigationalPovorcitinib is under investigation in clinical trial NCT06113445 (A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)).
Rezatapopt
go.drugbank.com/drugs/DB18980InvestigationalRezatapopt is under investigation in clinical trial NCT04585750 (The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)).
Synonyms: 4-[[3-[4-[[(3S,4R)-3-Fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methylbenzamide, Benzamide, 4-[[3-[4-[[(3S,4R)-3-fluoro-1-methyl-4-piperidinyl]amino]-1-(2,2,2-trifluoroethyl)-1H-indol-2-yl]-2-propyn-1-yl]amino]-3-methoxy-N-methyl-Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)
go.drugbank.com/drugs/DB14771InvestigationalPolyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
Synonyms: Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)Zorubicin
go.drugbank.com/drugs/DB11618ExperimentalZorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Synonyms: Benzoic acid hydrazide, 3-hydrazone with daunorubicinIlorasertib
go.drugbank.com/drugs/DB11694InvestigationalIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea, 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea)Peficitinib
go.drugbank.com/drugs/DB11708InvestigationalPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Categories: Heterocyclic Compounds, 1-Ring