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WVE-003
go.drugbank.com/drugs/DB17870InvestigationalWVE-003 is an allele-selective antisense oligonucleotide that works to selectively reduce the toxic mutant huntingtin (mHTT) protein.[L46787]
PNT001
go.drugbank.com/drugs/DB18375InvestigationalPNT001 is a humanized IgG4 S228P monoclonal antibody targeting the cis conformation of the phosphorylated Thr231-Pro232 motif in tau.
AVB-001
go.drugbank.com/drugs/DB18452InvestigationalAVB-001 is an encapsulated, engineered human ARPE-19 cell line that constitutively expresses the native human IL-2 cytokine
BBT-877
go.drugbank.com/drugs/DB18668InvestigationalBBT-877 is an autotaxin enzyme inhibitor being investigated for the treatment of fibrotic diseases, such as idiopathic pulmonary fibrosis.
Arasertaconazole
go.drugbank.com/drugs/DB19151InvestigationalArasertaconazole is under investigation in clinical trial NCT01144286 (Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatment).
Petrelintide
go.drugbank.com/drugs/DB19442InvestigationalPetrelintide is under investigation in clinical trial NCT06662539 (Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities).
Synonyms: 3,8-anhydro[N-(19-carboxynonadecanoyl)- L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L -lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-(2S)-α-2-aminoadipyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-arginyl, L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-5-carboxy-L-norvalyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-argiNevanimibe
go.drugbank.com/drugs/DB16254InvestigationalNevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
3-Methylthiofentanyl
go.drugbank.com/drugs/DB01439ExperimentalIllicit3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Orbifloxacin
go.drugbank.com/drugs/DB11443ExperimentalVet approvedIt is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Basimglurant
go.drugbank.com/drugs/DB11833InvestigationalBasimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.