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Midomafetamine
go.drugbank.com/drugs/DB01454IllicitInvestigationalAn N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates5-androstenedione
go.drugbank.com/drugs/DB01456ExperimentalIllicit5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its use in athletes is pr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCathine
go.drugbank.com/drugs/DB01486ExperimentalIllicitCathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug with stimulant properties. It belongs to the phenethylamine and amphetamine chemical classes. In the United States, it is classified as a Sche...
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnFenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and liste...
Products: P.Sulfamethazine
go.drugbank.com/drugs/DB01582ApprovedVet approvedWithdrawnA sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Synonyms: (p-Aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin, 2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidineUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigationalUrsodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. UDCA has been used to treat liver disease for decades: its first use in traditional me...
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalEverolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a simi...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesImipenem
go.drugbank.com/drugs/DB01598ApprovedInvestigationalImipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-la...
Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalTazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a vari...
Mixtures: AUROTAZ-P 4.5 G, Aurotaz-P Powder for Injections 4.5 gZuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalZuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates