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TC-2696
go.drugbank.com/drugs/DB05576ExperimentalSynonyms: 5-(5-METHOXY-3-PYRIDINYL)-N-METHYL-4-PENTEN-2-AMINE, (2S,4E)-Tadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigationalTadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment
Synonyms: (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dioneMixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCDD-0102
go.drugbank.com/drugs/DB16945ExperimentalSynonyms: 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine, Pyrimidine, 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydro-Categories: Receptor, Muscarinic M1, agonists, Heterocyclic Compounds, 1-RingTelbivudine
go.drugbank.com/drugs/DB01265ApprovedWithdrawnTelbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus.
Categories: Heterocyclic Compounds, 1-Ring, Hepatitis B Virus Nucleoside Analog Reverse Transcriptase InhibitorSynonyms: 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil, β-L-2'-deoxythymidine5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
go.drugbank.com/drugs/DB07141ExperimentalSynonyms: 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamineOxibendazole
go.drugbank.com/drugs/DB04910ExperimentalVet approvedOxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Methyl 5-n-propoxy-2-benzimidazole carbamate, Methyl 5-propoxy-2-benzimidazolecarbamateEniluracil
go.drugbank.com/drugs/DB03516Investigationals most widely-used oncology agents. 5-FU is widely used in the U.S. and is often first or second line therapy for a variety of cancers including colorectal, breast, gastric, head and neck, ovarian and … Eniluracil has received Orphan Drug status from the FDA for the treatment of hepatocellular cancer in combination with fluoropyrimidines (including 5-FU).
Synonyms: 5-EthynyluracilCategories: Heterocyclic Compounds, 1-RingBufotenine
go.drugbank.com/drugs/DB01445ExperimentalIllicitBufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.
Categories: N,N-Dimethyltryptamine, Serotonin 5-HT1 Receptor AntagonistsSynonyms: 5-hydroxy-N,N-dimethyltryptamine, N,N-dimethylserotonin1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
go.drugbank.com/drugs/DB07789ExperimentalSynonyms: 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]ureaWNT-974
go.drugbank.com/drugs/DB12561InvestigationalWNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (2,4'-bipyridine)-5-acetamide, 2',3-dimethyl-N-(5-(2-pyrazinyl)-2-pyridinyl)-