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IL21120033
go.drugbank.com/drugs/DB32508ExperimentalIL21120033 is a first-in-class, small-molecule selective CXCR7 agonist.
α-Methylfentanyl
go.drugbank.com/drugs/DB01557ExperimentalIllicitα-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
D-Leucine
go.drugbank.com/drugs/DB01746ExperimentalAn essential branched-chain amino acid important for hemoglobin formation. [PubChem]
Roluperidone
go.drugbank.com/drugs/DB13080InvestigationalRoluperidone has been used in trials studying the treatment of Schizophrenia.
AAV9/MFSD8
go.drugbank.com/drugs/DB18616ExperimentalAAV9/MFSD8 is a gene therapy developed by Neurogene Inc. … It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8
Synonyms: An adeno-associated virus serotype 9 (AAV9) vector with engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)-
go.drugbank.com/drugs/DB16204Investigationalthe Reduction of Inflammation in Patients With Active Rheumatoid Arthritis). … Isoquinoline, 7-(2-(3,6-dihydro-4-(3-(trifluoromethyl)phenyl)-1(2h)-pyridinyl)ethyl)- is under investigation in clinical trial NCT00545454 (Activity and Safety of Oral Administration of SSR150106XB for
Sovleplenib
go.drugbank.com/drugs/DB17557InvestigationalIt is under investigation in clinical trial NCT03483948 (Phase I Study of Hmpl-523+azacitidine in Elderly Patients With Acute Myeloid Leukemia). … Sovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting spleen tyrosine kinase (Syk).
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalAs of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine. … The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration.
Mephenytoin
go.drugbank.com/drugs/DB00532ApprovedWithdrawnMephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. … Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures.
Deoxyribonuclease I
go.drugbank.com/drugs/DB16523InvestigationalDeoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723]. … Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19).