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Hydroxyfasudil
go.drugbank.com/drugs/DB04707ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol
go.drugbank.com/drugs/DB04776ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: (2R)-2-({6-[Benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-1-butanol, (2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-olTanaproget
go.drugbank.com/drugs/DB04787ExperimentalAn analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging of the PR in positron emission tomography. … It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingVirginiamycin S1
go.drugbank.com/drugs/DB04805ExperimentalOne of the components of virginiamycin, a cyclic polypeptide antibiotic complex from streptomyces virginiae, s. Loidensis, s. Mitakaensis, s. Pristina-spiralis, s. Ostreogriseus, and others. … It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.
Synonyms: Staphylomycin S, Virginiamycin factor SBenoxaprofen
go.drugbank.com/drugs/DB04812ApprovedWithdrawnThe holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Synonyms: (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid, 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acidIproniazid
go.drugbank.com/drugs/DB04818ApprovedWithdrawnWithdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingNialamide
go.drugbank.com/drugs/DB04820ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Synonyms: 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine, N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazineCategories: Heterocyclic Compounds, 1-RingOxyphenisatin
go.drugbank.com/drugs/DB04823ApprovedWithdrawnA laxative that undergoes enterohepatic circulation. It may cause jaundice.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3,3-Bis(p-hydroxyphenyl)-2-indolinone, 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-2H-indol-2-oneThenalidine
go.drugbank.com/drugs/DB04826ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Synonyms: 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine, 1-Methyl-4-N-2-thenylanilinopiperidineCategories: Heterocyclic Compounds, 1-RingTienilic acid
go.drugbank.com/drugs/DB04831ApprovedWithdrawnTienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid, 4-(2-Theonyl)-2,3-dichlorphenoxyessigsäure