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Pristimerin
go.drugbank.com/drugs/DB17049ExperimentalPristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.[A253107]
TPCA-1
go.drugbank.com/drugs/DB17058ExperimentalTPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]
Sepantronium
go.drugbank.com/drugs/DB17062InvestigationalSepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.[A253167]
JNJ-17216498
go.drugbank.com/drugs/DB17087InvestigationalJNJ-17216498 is a histamine receptor H3 antagonist developed by Johnson and Johnson for the treatment of narcolepsy.[A253997]
KT-333
go.drugbank.com/drugs/DB17165InvestigationalKT-333 is a small molecule targeted protein degrader of STAT3.[L44086]
Diaziquone
go.drugbank.com/drugs/DB17174ExperimentalCategories: Compounds used in a research, industrial, or household settingOS2966
go.drugbank.com/drugs/DB17207InvestigationalOS2966 is a humanized integrin β1 (CD29) blocking antibody currently evaluated for the treatment of acute myeloid leukemia, glioblastoma and ovarian cancer.[A254561, L47351]
PRGN-3006
go.drugbank.com/drugs/DB17229InvestigationalPRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface
Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surfaceST-36
go.drugbank.com/drugs/DB17275ExperimentalST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341]