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Cardiolipin Biosynthesis CL(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:2(11Z,14Z)/16:0)
smpdb.ca/view/SMP0287987MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Saxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Synonyms: (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrileMixtures: KOMBIGLYZE ® XR 5 MG/ 1000 MG, KOMBIGLYZE® XR2.5 MG/1000 MGErgoloid mesylate
go.drugbank.com/drugs/DB01049Approved[A32912] All these components are produced by the fungus _Claviceps purpurea_ and are all derivatives of the tetracyclic compound 6-methylergonovine. … [A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued.
Categories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesProducts: SEGOL 1 MG/ML DAMLA, ÇÖZELTİ, 50 ML, อินเดอร์จิน 1 มก.Maribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigational[L39327] The drug was also approved by Health Canada in September 2022 [L43262] and by European Commission in November 2022.[L44411] … Maribavir was approved by the FDA in November 2021, under the name Livtencity (Takeda), for the treatment of resistant CMV infections in post-transplant patients.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet), Livtencity 200 mg Film Kaplı Tablet (56 Adet)Chloral hydrate
go.drugbank.com/drugs/DB01563ApprovedIllicitInvestigationalVet approvedA hypnotic and sedative used in the treatment of insomnia. … The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments.
Products: PMS-CHLORAL HYDRATE SYRUP 500 mg/5 ml, PMS-chloral Hydrate Syrup 100mg/mlCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnLike spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: Aldactone 200 mg/ 10 ml Injektionslösung, POTASSIO CANRENOATO EGDecoquinate
go.drugbank.com/drugs/DB11394ExperimentalVet approvedDecoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Categories: Heterocyclic Compounds, 2-RingProducts: Deco 6% w/w Premix Powder, DECCOX ® POWDER 6% w/wNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] It is also available in combination with [relatlimab] under the brand name Opdualag.[L41265,L49996,L50001]
Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: Immunoglobulin G, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsStage IV Non-small Cell Lung Cancer (NSCLC)
go.drugbank.com/conditions/DBCOND0122752Drugs: GemcitabineSynonyms: Stage 4 NSCLC, Stage 4 Non-small cell lung cancerFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Synonyms: 5-FC, 5-FluorocytosineCategories: Heterocyclic Compounds, 1-Ring