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HTPEP-001
go.drugbank.com/drugs/DB18730ExperimentalHTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-β). It is being investigated for the treatment of fibrosis.[A263527]
BVX-001
go.drugbank.com/drugs/DB18733ExperimentalBVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
Bepirovirsen
go.drugbank.com/drugs/DB16202InvestigationalIONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).
Ivuxolimab
go.drugbank.com/drugs/DB16208InvestigationalIvuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Synonyms: Anti-OX40 Antibody PF-04518600Ladarixin
go.drugbank.com/drugs/DB16212InvestigationalLadarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).
Apinocaltamide
go.drugbank.com/drugs/DB16241InvestigationalApinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
MK-0773
go.drugbank.com/drugs/DB16244InvestigationalMK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)).
Nafithromycin
go.drugbank.com/drugs/DB16246InvestigationalNafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsOsalmid
go.drugbank.com/drugs/DB16273InvestigationalOsalmid is under investigation in clinical trial NCT03670173 (Safety and Efficacy Assessments of Osalmid in Multiple Myeloma).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesOsoresnontrine
go.drugbank.com/drugs/DB16274InvestigationalOsoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks