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Mepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalMepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline. … The pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue
Categories: Amino Acids, Peptides, and ProteinsProducts: NUCALA® 100MG/ML SOLUCION INYECTABLE, NUCALA POWDER FOR SOLUTION FOR INJECTION 100mgDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
go.drugbank.com/bio_entities/BE0001300TargetHumansMay act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K
Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositideArtemisia vulgaris pollen
go.drugbank.com/drugs/DB10372ApprovedArtemisia vulgaris pollen is the pollen of the Artemisia vulgaris plant. Artemisia vulgaris pollen is mainly used in allergenic testing.
Categories: Non-Standardized Pollen Allergenic ExtractProducts: Pollens - Weeds and Garden Plants, Sagebrush, Mugwort Artemisia vulgarisBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[L4779] It was also approved by the European Commission on January 7, 2021.[L45241] … Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Categories: Baloxavir and prodrugsProducts: XOFLUZA FILM COATED TABLETS 20MG, XOFLUZA FILM-COATED TABLET 20MGParecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalA letter of non-approval for parecoxib was issued by the FDA in 2005. … Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic ProductsSynonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamideIndocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalEach vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide. … Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm.
Products: Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint, Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and PinpointFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity.
Categories: Calcium-Regulating Hormones and AgentsProducts: NATIL N 10MG, NATIL N 5MGPhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigationalThis initial product, formed by the combination of phentermine with [fenfluramine] and [dexfenfluramine] was discontinued after finding several reports of abnormal valves in nearly 30% of the consumers … [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.
Mixtures: Phentermine and topiramate, Phentermine and topiramateCategories: Alimentary Tract and Metabolism, phentermine and topiramatePenicillamine
go.drugbank.com/drugs/DB00859ApprovedInvestigationalIt is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Categories: Amino Acids, Peptides, and Proteins, Penicillamine and Similar AgentsProducts: Depen Tab 250mg, ARTAMIN CAPSULE 250MGPine needle oil (pinus mugo)
go.drugbank.com/drugs/DB11276ApprovedIt is present in aromatherapeutic agents as a massage oil or fragrance and may also be used as a disinfectant, lubricant, sanitizer, antimicrobial, insecticide and organic herbicide. … Major components of pine needle oil (pinus mugo) include α-Pinene, β-pinene, δ-3-carene, limonene, β-phellandrene, (E)-caryophyllene, and germacrene D.
Mixtures: Co CoolCategories: Herbs and Natural Products