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Rasburicase
go.drugbank.com/drugs/DB00049ApprovedInvestigationalRasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified <i>Saccharomyces cerevisiae</i> strain.
Products: FASTURTEC 7,5 MG/5 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1ADET, FASTURTEC 1,5 MG/1 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADETRisdiplam
go.drugbank.com/drugs/DB15305ApprovedInvestigational[L15331,L15336] Set to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a novel and relatively accessible treatment option for patients with SMA regardless … This mechanism of action is similar to its predecessor [nusinersen], the biggest difference being their route of administration: nusinersen requires intrathecal administration, as does the one-time gene
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: Evrysdi 0,75 mg/mL Oral Çözelti Hazırlamak İçin Toz, 80 ML, Evrysdi Powder for oral solution 0.75 mg/mLChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A191655] It was the drug of choice to treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and [mefloquine].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADET, KUTLU 250 MG FİLM KAPLI TABLET, 10 ADETSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalSiltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). … MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: SYLVANT 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET, SYLVANT 400 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADETProtamine
go.drugbank.com/drugs/DB13700ApprovedInvestigationalWithdrawnProducts: PROTAMYN 1000® UI/ML AMPOLLA, Protamin Meda 1000 I.E./ml - InjektionslösungRaltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalRaltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Products: Chewable Tablet 100 mg, ISENTRESS 400 MG FILM KAPLI TABLET, 60 ADETApremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalIt belongs to the same drug class as [Roflumilast] and [Crisaborole].[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases.
Mixtures: OTEZLA (10 MG 20 MG 30 MG), OTEZLA (10 MG 20 MG 30 MG)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approvedHydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]
Mixtures: Activir Duo 50 mg/g + 10 mg/g Creme, Oto End 10Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersPropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: RYTMONORM 150 MG, RYTMONORM TABLET 150 mgCinrebafusp alfa
go.drugbank.com/drugs/DB18402InvestigationalSynonyms: ALANINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN PEPTIDE (SYNTHETIC 15-AMINO ACID LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU, IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2, ERBB2, HER2)) FUSED ON BOTH HEAVY CHAINS (1-447, 1''-447'') VIA A (G4S)3 LINKER (448-462, 448''-462'') TO