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Vinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigational(Merck, 11th ed.)
Categories: Heterocyclic Compounds, 2-RingProducts: VINCABLAS® 10 MG/VIAL, VINBLASTINA SULFATO 10 MGCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.
Synonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideProducts: ALKYLOXAN INJ 200 MG FLAKON, 1 ADET, ENDOXAN 50 MG KAPLI TABLET, 30 ADETPovidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnin eye drops. … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Synonyms: 1-vinyl-2-pyrrolidinone polymer, 1-ethenyl-2-pyrrolidinone homopolymerMixtures: FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, Leader Artificial Tears 15 mLQuinidine
go.drugbank.com/drugs/DB00908ApprovedThis alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. … A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal attacks and ventricular fibrillation in patients treated with this drug.
Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 2-RingSynonyms: (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol, (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanolCalcium carbonate
go.drugbank.com/drugs/DB06724ApprovedInvestigationalCalcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Synonyms: Calcium carbonate (1:1), Carbonic acid calcium salt (1:1)Mixtures: CALCIUM-D SANDOZ 600 MG/400 IU 20 EFERVESAN TABLET, 20 ADET, PRONAT 500 mg+267 mg+160 mg/10 ml ORAL SÜSPANSIYON, 200 MLEpinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepineNateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADET, NAT-ALA 180/200 MG FILM KAPLI TABLET, 90 ADETCategories: Drugs Used in DiabetesMetandienone
go.drugbank.com/drugs/DB13586ApprovedWithdrawnMetandienone is an orally active anabolic androgenic steroid. It was introduced to the market in the 1960s but later discontinued and withdrawn from the market. … Although it is prohibited in and outside competition by the World Anti-Doping Agency, metandienone continues to be marketed and misused as a performance-enhancing drug in sports.
Products: SIROBOLIN ŞURUP, 120 ML, เมตาโบลอน 20Capecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. … Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Synonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamateCategories: Heterocyclic Compounds, 1-RingRanibizumab
go.drugbank.com/drugs/DB01270ApprovedInvestigational[A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission (EC) in 2007.[L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. … [L41399] In August 2022, other biosimilars CIMERLI, RAIVISIO, and RANOPTO were approved by the FDA, EC, and Health Canada respectively.[L42625,L43513,L49141]
Products: LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE, LUCENTIS® 10 MG /ML SOLUCION INYECTABLE