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Pegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigational[L34095] In February 2023, pegcetacoplan for intravitreal use was approved by the FDA for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration.[L45354] … [A235000] Pegcetacoplan for subcutaneous use was granted FDA approval on 14 May 2021.
Fibrinolysin
go.drugbank.com/drugs/DB05254InvestigationalThe ointment is marketed by Pfizer under the brand name Fibrolan in a variety of countries (e.g. Switzerland). It is currently not approved in the USA. … The light chain has a molecular weight of approximately 27,000 Da and contains the active center of Fibrinolysin; the heavy chain has a molecular weight of approximately 57,000 Da.
Mixtures: FIBRASE SANicoboxil
go.drugbank.com/drugs/DB12911ApprovedWithdrawnSuch combination topical analgesics are only available for purchase and use (for humans) in some parts of Europe and Asia, like Germany and Australia [F11, F16]. … Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately synergistic
Iron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigational(hemodialysis or peritoneal) and those who do not require dialysis. … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
Mixtures: Bal-Care DHA, Choice OB DHAProducts: HIERRO SACARATO EQUIVALENTE A HIERRO ELEMENTAL 100 MG/ 5ML.Isatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigational[L12099,L12102] It is manufactured by Sanofi-Aventis U.S. under the brand name Sarclisa.[L12102] … Isatuximab (formerly SAR650984) is a humanized, IgG1-derived monoclonal antibody (mAb) produced from a Chinese hamster ovary (CHO) cell line.
Linaclotide
go.drugbank.com/drugs/DB08890ApprovedInvestigational[A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first natural ligand that activates GC-C. … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist.
Flupirtine
go.drugbank.com/drugs/DB06623InvestigationalFlupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe.
Sodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalLike citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing agent. It works by neutralizing excess acid in the blood and urine.
Mixtures: A-C-D Solution, DONEXAN DXCategories: Compounds used in a research, industrial, or household settingGallium Ga-68 gozetotide
go.drugbank.com/drugs/DB16019ApprovedInvestigationalGallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions … [L27006] On December 1, 2020, Ga-68 PSMA-11 was approved by the FDA as the first molecular-targeted drug for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA)
Categories: Compounds used in a research, industrial, or household settingSynonyms: Ga-Psma-hbed-CC Ga-68, Ga PSMAOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigational[A189336] In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard … [L41524] In November 2021, ozanimod was also approved by the European Commission for the treatment of adults with relapsing remitting multiple sclerosis.
Mixtures: ZEPOSIA 7-Day Starter Pack, ZEPOSIA 7-Day Starter Pack