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Atecegatran metoxil
go.drugbank.com/drugs/DB12507InvestigationalAtecegatran metoxil has been used in trials studying the basic science and prevention of Nonvalvular Atrial Fibrillation, Persistent or Permanent Nonvalvular Atrial Fibrillation, and Persistent or Permanent
Categories: Heterocyclic Compounds, 1-RingZR202-CoV
go.drugbank.com/drugs/DB27995InvestigationalZR202-CoV is a biologic drug. ZR202-CoV is under investigation in clinical trial NCT05490108 (Evaluation of Safety and Immunogenicity of the Recombinant ZR202-CoV and ZR202a-CoV Vaccines in Adults.).
ACCG-2671
go.drugbank.com/drugs/DB33945ExperimentalACCG-2671 is a small molecule drug. ACCG-2671 is under investigation in clinical trial NCT07815678 (First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671).
Quinolinic Acid
go.drugbank.com/drugs/DB01796ExperimentalA metabolite of tryptophan with a possible role in neurodegenerative disorders. … Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem]
Categories: Heterocyclic Compounds, 1-RingTrastuzumab botidotin
go.drugbank.com/drugs/DB17413ExperimentalA166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable
Synonyms: Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5Zodasiran
go.drugbank.com/drugs/DB17626InvestigationalIt was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia (HoFH).[L45869] … ARO-ANG3 is a subcutaneously administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 (ANGPTL3).
AZD-8186
go.drugbank.com/drugs/DB15029InvestigationalBe Removed by Surgery). … AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingIopofosine I-131
go.drugbank.com/drugs/DB15244InvestigationalIopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).
Synonyms: Ethanaminium, 2-((hydroxy((18-(4-(iodo-131I)phenyl)octadecyl)oxy)phosphinyl)oxy)-N,N,N-trimethyl-, inner salt, 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALTFlurazepam
go.drugbank.com/drugs/DB00690ApprovedIllicitA benzodiazepine derivative used mainly as a hypnotic.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesNitarsone
go.drugbank.com/drugs/DB11437ExperimentalVet approvedNitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. … It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Synonyms: (p-nitrophenyl)arsonic acid, 4-nitrobenzenearsonic acid