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Displaying results 961 - 970 of 10000 in total
  1. Drug

    Gadoteric acid

    go.drugbank.com/drugs/DB09132
    ApprovedInvestigational

    [A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 for intravenous uses with magnetic resonance imaging (MRI) in the brain (intracranial), spine, and … Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA).

    Categories: Compounds used in a research, industrial, or household settingProducts: DOTAREM INJECTION (10ML VIAL), CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML
  2. Drug

    Lacidipine

    go.drugbank.com/drugs/DB09236
    Approved

    It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure. … Compared to other dihydropyridine calcium antagonists, lacidipine exhibits a greater antioxidant activity which may confer potentially beneficial antiatherosclerotic effects [A31540].

    Products: LACIDIPINA EG
  3. Drug

    Dexlansoprazole

    go.drugbank.com/drugs/DB05351
    Approved

    [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production by blocking the (H+, K+)-ATPase enzyme.[L48827] … Compared to the older generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084] dexlansoprazole has a unique pharmacokinetic profile due to its delayed-release and dual-delivery

    Products: DELAXISE 30 MG EC RETARD TABLET, 30 ADET, DELAXISE 60 MG EC RETARD TABLET, 30 ADET
  4. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...

    Mixtures: Theophylline in Dextrose, Theophylline in DextroseProducts: Theochron Srt 100mg, Theo ER
  5. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].

    Categories: Compounds used in a research, industrial, or household settingProducts: ALCOHOL POLIVINÍLICO 14MG/ML SOLUCIÓN OFTÁLMICA, Cooper Tears
  6. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. … Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].

    Mixtures: OCTILIA ALLERGIA E INFIAMMAZIONE, OCTILIA ALLERGIA E INFIAMMAZIONEProducts: FENAMED 45,5 MG/2 ML IM/IV ENJ. COZ. ICEREN 50 AMPUL, FENAMED 45,5 MG/2 ML IM/IV ENJ. COZ. ICEREN AMPUL, 5 ADET
  7. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Mixtures: FOLISTER COMPLEX HAIR LOTION (R), FOLISTER COMPLEX HAIR LOTION (R)Categories: Arteriolar Smooth Muscle, Agents Acting On
  8. Drug

    Nicardipine

    go.drugbank.com/drugs/DB00622
    ApprovedInvestigational

    It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem] … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects.

    Products: Nicardipine Hydrochloride in Sodium Chloride, Nicardiin 1mg/ml Solution for Infusion
  9. Drug

    Tiapride

    go.drugbank.com/drugs/DB13025
    Investigational

    Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.

    Products: TIAPRID HEXAL 100MG, TIAPRID STADA 100MG
  10. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis. … [A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer.

    Products: TARCKORIN ® 100MG, CAMPTO 100MG/5ML INJECTION