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Displaying results 961 - 970 of 10000 in total
  1. Pathway

    Mirabegron Action Pathway

    smpdb.ca/view/SMP0126105
    Drug action

    Mirabegron is a beta-3 adrenergic receptor agonist that is used to treat overactive bladder and neurogenic detrusor activity. It relaxes the smooth muscle of the bladder which expands the bladder to relieve urgency. It is an oral medicat...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Mirabegron
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  2. Pathway

    Gs Histaminic Smooth Muscle Relaxation

    smpdb.ca/view/SMP0126967
    Physiological

    The Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα is the foundin...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  3. Pathway

    Celiprolol B2-Adrenergic Vasodilation Action Pathway

    smpdb.ca/view/SMP0126095
    Drug action

    Celiprolol is a selective beta-1 adrenergic receptor antagonist and a beta-2 adrenergic receptor partial agonist that is used for the management of hypertension and angina pectoris. The beta-2 adrenergic receptor agonist activity is attr...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Celiprolol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  4. Pathway

    Fenoterol Action Pathway

    smpdb.ca/view/SMP0126100
    Drug action

    Fenoterol is a short acting beta-2 adrenergic receptor agonist that is used as a bronchodilator. This drug causes the relaxation of bronchial smooth muscle allowing for its use for the treatment of asthma. The result of taking this drug ...

    Drugs: ATP · Fenoterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  5. Pathway

    Pirbuterol Action Pathway

    smpdb.ca/view/SMP0126102
    Drug action

    Pirbuterol is a beta-2 adrenergic agonist that has a preferential effect. It is a short acting, inhaled drug that causes bronchial smooth muscle relaxation through stimulation of adenylyl cyclase. It is used as a bronchodilator for the t...

    Drugs: ATP · Pirbuterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  6. Pathway

    Racepinephrine B2-Adrenergic Bronchodilation Action Pathway

    smpdb.ca/view/SMP0126107
    Drug action

    Racepinephrine is a bronchodilator used to treat asthma. It can be found under the brand name Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a rapid onset and short duration and acts ...

    Drugs: ATP · Epinephrine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  7. Pathway

    Etafedrine Action Pathway

    smpdb.ca/view/SMP0126114
    Drug action

    Etafedrine is a beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa. It can be found under the brand name Dalmacol and is a long acting bronchodilator that relaxes the smooth muscle of the lungs. It can be u...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  8. Pathway

    Orciprenaline Action Pathway

    smpdb.ca/view/SMP0126083
    Drug action

    Orciprenaline is a beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. This drug is used exclusively as a bronchodilator. When taken, it acts on the smooth muscles in the bronchi causing a muscle relaxation or broncho...

    Drugs: ATP · Orciprenaline · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  9. Pathway

    Salmeterol Action Pathway

    smpdb.ca/view/SMP0126085
    Drug action

    Salmeterol is a long acting beta-2 adrenergic receptor agonists used to treat asthma and COPD. Beta-2 agonists are G protein linked second messengers. It can be found under the brand names Advair, Airduo, Serevent, and Wixela. This drug ...

    Drugs: ATP · Salmeterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  10. Pathway

    Indacaterol Action Pathway

    smpdb.ca/view/SMP0126090
    Drug action

    Indacaterol is an inhaled beta-2 adrenergic agonist that is both rapid onset and long acting. The purpose of this drug is to relax bronchial smooth muscle to help treat COPD, asthma, and chronic bronchitis by opening the airways. It can ...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Indacaterol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12