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Macimorelin
go.drugbank.com/drugs/DB13074ApprovedThey include treatment for growth retardation in children and cachexia associated with chronic disease such as AIDS and cancer. … Macimorelin, developed by Aeterna Zentaris, was approved by the FDA in December 2017 under the market name Macrilen for oral solution.
Categories: Tests for Pituitary FunctionGrazoprevir
go.drugbank.com/drugs/DB11575Approvedin combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593]. … When combined together, Grazoprevir and [DB11574] as the combination product Zepatier have been shown to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseAlitretinoin
go.drugbank.com/drugs/DB00523ApprovedIt has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute). … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic.
Categories: Retinoids for cancer treatment, Agents for Dermatitis, Excluding CorticosteroidsHexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalFood and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as an optical imaging agent for use in combination with the … Karl Storz Photodynamic Diagnostic D-Light C (PDD) System for cystoscopic detection of non-muscle invasive papillary cancer of the bladder for patients suspected or known to have lesion(s) on the basis
Candesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalIt may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease. … Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents
Categories: Antihypertensive Agents Indicated for HypertensionSodium phosphate, monobasic
go.drugbank.com/drugs/DB09449ApprovedInvestigationalSodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Mixtures: FLEET ENEMA FOR CHILDREN, OMEGA PLUS EMULSION FOR INFUSIONCategories: Drugs for Constipation, Drugs for Treatment of HypercalcemiaDemeclocycline
go.drugbank.com/drugs/DB00618ApprovedBecause it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Categories: Antibiotics for Topical Use, Antibacterials for Systemic UseZiftomenib
go.drugbank.com/drugs/DB17171ApprovedInvestigational[L54601] Ziftomenib works by preventing the protein-protein interaction between menin and KMT2A, a complex essential for maintaining the proliferation and survival of these leukemic cells. … [A274738] This drug was approved by the FDA on November 13th, 2025, for the treatment of relapsed or refractory acute myeloid leukemia (AML) in adults with a susceptible NPM1 mutation who have no satisfactory
Abatacept
go.drugbank.com/drugs/DB01281ApprovedInvestigationalAlthough approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077).
Categories: Biologics for Rheumatoid Arthritis TreatmentRebamipide
go.drugbank.com/drugs/DB11656ApprovedInvestigationalRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)