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Sulfapyridine
go.drugbank.com/drugs/DB00891ApprovedWithdrawnAntibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Synonyms: 4-Amino-N,2-pyridinylbenzenesulfonamide, 4-Amino-N-pyridin-2-yl-benzenesulfonamideCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsLuvixasertib
go.drugbank.com/drugs/DB19200InvestigationalLuvixasertib is under investigation in clinical trial NCT05251714 (CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer).
Synonyms: Benzamide, n-cyclopropyl-4-(7-(((cis-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(3-pyridinyloxy)pyrazolo(1,5-a)pyrimidin-3-yl)-2-methyl-, N-cyclopropyl-4-(7-(((cis-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(3-pyridinyloxy)pyrazolo(1,5-a)pyrimidin-3-yl)-2-methylbenzamideCategories: Heterocyclic Compounds, 1-RingHydroxyproline
go.drugbank.com/drugs/DB08847ApprovedHydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. … Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Synonyms: trans-4-Hydroxy-L-proline, trans-L-HydroxyprolineMixtures: Gongjinhyang Mi Luxury Foundation 2, Gongjinhyang Mi Luxury Foundation 14-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol
go.drugbank.com/drugs/DB04407ExperimentalSynonyms: 4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-PhenolMethyl-[4-(4-Piperidine-1-Ylmethyl-Phenyl)-Cyclohexyl]-Carbaminic Acid-(4-Chlorophenyl)-Ester
go.drugbank.com/drugs/DB03748ExperimentalSynonyms: Methyl-[4-(4-Piperidine-1-Ylmethyl-Phenyl)-Cyclohexyl]-Carbaminic Acid-(4-Chlorophenyl)-EsterIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Synonyms: 4-Demethoxydaunomycin, 4-DemethoxydaunorubicinCategories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexNalidixic acid
go.drugbank.com/drugs/DB00779ApprovedWithdrawnNalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Synonyms: 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure, 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-oneCategories: 4-Quinolones, Heterocyclic Compounds, 2-RingBarzuxetan
go.drugbank.com/drugs/DB21132ExperimentalBarzuxetan is a small molecule drug. The usage of the INN stem '-xetan' in the name indicates that Barzuxetan is a chelating agent. Barzuxetan has a monoisotopic molecular weight of 594.2 Da.
Synonyms: Chx-a''-dtpaTylosin
go.drugbank.com/drugs/DB11475ExperimentalVet approvedTylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. … It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.
Synonyms: Tylosin AMixtures: Tylan 40 Sulfa-G PremixPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma [L37674].
Synonyms: (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidCategories: Heterocyclic Compounds, 2-Ring