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Butamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnButamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. … The FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942]
Polyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPEGylation occurs when PEGs are attached to numerous protein medications, allowing for greater solubility for selected drugs. … It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye [L1785].
Mixtures: Visine ALL DAY COMFORT DRY EYE Relief, Visine for Red Eye CoolCategories: Compounds used in a research, industrial, or household settingErgocalciferol
go.drugbank.com/drugs/DB00153ApprovedInvestigationalNutraceuticalErgocalciferol was isolated for the first time from yeast in 1931 and its structure was elucidated in 1932. … These modifications reduce the affinity of ergocalciferol for the vitamin D binding protein resulting in faster clearance, limits its activation, and alters its catabolism.
Mixtures: Insur-all Vitamin Supplement, TAMIPOOL FOR INJECTIONTideglusib
go.drugbank.com/drugs/DB12129ApprovedInvestigationalWithdrawnTideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. … [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current status is withdrawn for the treatment of Alzheimer's disease as of 2012.
Entecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseD-alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14002ApprovedNutraceuticalVet approvedbioavailability out of all of the alpha-tocopherol stereoisomers. … At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.
Mixtures: Poly-Vi-Flor, Poly-VI-florCategories: Compounds used in a research, industrial, or household settingFluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approved[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies
Mixtures: PISAURIT FONCategories: Antidepressive Agents Indicated for DepressionVonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigationalPCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnAll of the derivatives have slight different physicochemical properties when compared to the parent structure. … [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]
Categories: Antibiotics for Topical Use, Antiinfectives for Systemic UseNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L11985] Neomycin sulfate is the most common form for pharmaceutical preparations; because the compound is a complex, the amount of neomycin in products is measured in units. … [A191529] Neomycin sulfate as monotherapy is available in an oral solution for adjunct use in the treatment of hepatic coma.
Mixtures: Equaline Antibiotic Plus Pain Relief for Kids, CVS Health All Purpose KitCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use