Search

Displaying results 9811 - 9820 of 10000 in total
  1. Drug

    Mosperafenib

    go.drugbank.com/drugs/DB21673
    Experimental

    The usage of the INN stem '-rafenib' in the name indicates that Mosperafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. Mosperafenib has a monoisotopic molecular weight of 461.1 Da.

  2. Drug

    Talopram

    go.drugbank.com/drugs/DB09190
    Experimental

    It was researched in the 1960s and 1970s but never marketed.

  3. Drug

    Oprozomib

    go.drugbank.com/drugs/DB11991
    Investigational

    Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS

  4. Drug

    Demegestone

    go.drugbank.com/drugs/DB13857
    Experimental

    It was previously marketed in France as Lutionex, but has since been discontinued.

  5. Drug

    Milatuzumab

    go.drugbank.com/drugs/DB12943
    Investigational

    Milatuzumab has been used in trials studying the treatment of Lupus Nephritis, Multiple Myeloma (MM), GVHD (Acute or Chronic), Myelodysplastic Syndrome, and Chronic Lymphocytic Leukemia, among others.

  6. Drug

    Rovalpituzumab tesirine

    go.drugbank.com/drugs/DB13017
    Investigational

    Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.

  7. Drug

    PEP0101

    go.drugbank.com/drugs/DB18572
    Experimental

    PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.

    Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.
  8. Drug

    TN-201

    go.drugbank.com/drugs/DB18700
    Investigational

    TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.

  9. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]

    Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide
  10. Drug

    JLK-247

    go.drugbank.com/drugs/DB17637
    Experimental

    JLK-247 is an adeno-associated viral vector serotype 9 (AAV9)-mediated gene replacement therapy for the treatment of Sanfilippo Syndrome Type C or MPS IIIC.[L46686]