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Displaying results 9821 - 9830 of 10000 in total
  1. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]

  2. Drug

    Meglutol

    go.drugbank.com/drugs/DB04377
    Experimental

    It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which … is the rate limiting enzyme in the biosynthesis of cholesterol.

  3. Drug

    Technetium Tc-99m

    go.drugbank.com/drugs/DB14227
    Investigational

    Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

  4. Drug

    Metampicillin

    go.drugbank.com/drugs/DB13836
    Experimental

    Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. … Hydrolysis is rapid under acid conditions like the stomach.

  5. Drug

    Ligufalimab

    go.drugbank.com/drugs/DB17542
    Investigational

    It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome). … Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47.

  6. Drug

    Zinpentraxin alfa

    go.drugbank.com/drugs/DB14852
    Investigational

    It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis). … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein.

  7. Drug

    Adermastat

    go.drugbank.com/drugs/DB28906
    Investigational

    Adermastat is a small molecule drug. … Adermastat is under investigation in clinical trial NCT03858686 (The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.).

  8. Drug

    Selodenoson

    go.drugbank.com/drugs/DB16325
    Investigational

    Selodenoson is under investigation in clinical trial NCT00040001 (Safety and Efficacy Study of an A1-adenosine Receptor Agonist to Slow Heart Rate in Atrial Fibrillation).

  9. Drug

    Imidocarb

    go.drugbank.com/drugs/DB11521
    ExperimentalVet approved

    Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.

    Synonyms: N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea
  10. Drug

    Methylprednisone

    go.drugbank.com/drugs/DB12952
    ApprovedInvestigationalWithdrawn

    Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.