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Choline alfoscerate
go.drugbank.com/drugs/DB04660InvestigationalA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.
Synonyms: sn-3-GPC, glycerol-3-phosphocholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADETCamptothecin
go.drugbank.com/drugs/DB04690InvestigationalCamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, <i>Camptotheca acuminata</i>. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I.
Categories: P-glycoprotein substrates, Topoisomerase I InhibitorsSynonyms: D-camptothecin, 20(S)-camptothecinegamma-Butyrolactone
go.drugbank.com/drugs/DB04699ExperimentalIllicitIt is also used as a pharmacological agent and solvent. … One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate.
Categories: 4-Butyrolactone, Heterocyclic Compounds, 1-RingSynonyms: 4-butyrolactone, γ-butyrolactoneCitraconic acid
go.drugbank.com/drugs/DB04734ExperimentalCitraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Synonyms: (Z)-2-Methyl-2-butenedioic acid, 2-Methyl-2-butenedioic acidLawsone
go.drugbank.com/drugs/DB04744ExperimentalSynonyms: 2-hydroxynaphthoquinone, 2-hydroxy-1,4-naphthoquinoneCategories: Compounds used in a research, industrial, or household settingPrenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Synonyms: 1-Phenyl-2-(1',1'-diphenylpropyl-3'-amino)propane, N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesClofedanol
go.drugbank.com/drugs/DB04837ApprovedWithdrawnClofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Mixtures: Certuss-D, biclora-DCediranib
go.drugbank.com/drugs/DB04849InvestigationalThe novel indole-ether quinazoline Cediranib is a highly potent (IC<sub>50</sub> < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. … It is being developed clinically as a once-daily oral therapy for the treatment of cancer.
Categories: Heterocyclic Compounds, 2-Ring, Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitorsPermethrin
go.drugbank.com/drugs/DB04930ApprovedInvestigationalA pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate, 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl esterCanfosfamide
go.drugbank.com/drugs/DB04972InvestigationalCanfosfamide is an active agent in chemotherapy-resistant ovarian cancer.