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Intoplicine
go.drugbank.com/drugs/DB12868InvestigationalIntoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
GsMtx-4
go.drugbank.com/drugs/DB17861InvestigationalGsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity.
DS-2325a
go.drugbank.com/drugs/DB18134InvestigationalDS-2325a is an inhibitor of kallikrein 5 under development for the treatment of Netherton Syndrome.
Methfuroxam
go.drugbank.com/drugs/DB16231InvestigationalMethfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma).
Sasanlimab
go.drugbank.com/drugs/DB18849InvestigationalSasanlimab is under investigation in clinical trial NCT06218069 (Immuno-pet Imaging Responses Administered Immune Checkpoint Inhibitor).
Apararenone
go.drugbank.com/drugs/DB15024InvestigationalApararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).
Psicose
go.drugbank.com/drugs/DB15087ExperimentalPsicose is under investigation in clinical trial NCT02459834 (The Fructose and Allulose Catalytic Effects (FACE) Trial).
GLPG-0259
go.drugbank.com/drugs/DB15190InvestigationalGLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
NKG2D-ACE2 CAR-NK Cell
go.drugbank.com/drugs/DB15727InvestigationalChimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling moieties. … The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity.
CoronaVac
go.drugbank.com/drugs/DB15806InvestigationalIn preclinical trials, PiCoVacc induced SARS-CoV-2-specific neutralizing antibodies in rats, mice, and the rhesus macaque. … As of August 2020, the vaccine is being tested in numerous human clinical trials assessing its safety and immunogenicity.