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Displaying results 981 - 990 of 7181 in total
  1. Drug

    Risperidone

    go.drugbank.com/drugs/DB00734
    ApprovedInvestigational

    [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways … [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Nu-risperidone, Nb-risperidone
  2. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … [A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Nu-mirtazapine, Co Mirtazapine
  3. Drug

    Burosumab

    go.drugbank.com/drugs/DB14012
    ApprovedInvestigational

    This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of rickets. … Most children with XLH suffer from bowed or bent legs, short stature, bone pain and severe dental pain.

  4. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy [L5200]. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the

    Products: DIAZEPAM RATIO 10MG/ML TRO
  5. Drug

    Glycyrrhizic acid

    go.drugbank.com/drugs/DB13751
    ApprovedInvestigational

    [F80] It was approved by Health Canada to be used in over-the-counter products but all the products are currently on the status canceled post marketed.[L1113] … [A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener.

    Mixtures: Quick-Acting Wart Removal
  6. Drug

    Fumaric acid

    go.drugbank.com/drugs/DB01677
    Investigational

    Synonyms: trans-but-2-enedioic acid
  7. Indication

    Aspiration Pneumonitis

    go.drugbank.com/conditions/DBCOND0075845
    Drugs: Cortisone acetate · Dexamethasone · Hydrocortisone · Methylprednisolone · Prednisolone · Prednisone
    Synonyms: Pneumonitis due to inhalation of food and vomit
  8. Indication

    Toxocariasis

    go.drugbank.com/conditions/DBCOND0009840
    Drugs: Mebendazole
    Synonyms: Infection due to toxocara
  9. Drug

    Elinzanetant

    go.drugbank.com/drugs/DB18968
    ApprovedInvestigational

    [A274198] On July 23, 2025, it was approved by Health Canada to treat moderate to severe vasomotor symptoms (VMS) associated with menopause. … [L53798] By blocking receptor signaling on kisspeptin/neurokinin B/dynorphin (KNDy) neurons, which are hyperactivated due to estrogen decline in menopause, elinzanetant modulates neuronal activity involved

    Synonyms: 2-(3,5-bis(trifluoromethyl)phenyl)-n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-7-(hydroxymethyl)hexahydropyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,2-dimethylpropanamide, Benzamide, 3-(5-methyl-2-tbenzeneacetamide, n-(4-(4-fluoro-2-methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha.,.alpha.
  10. Indication

    Rocky Mountain Spotted Fever

    go.drugbank.com/conditions/DBCOND0000434
    Drugs: Minocycline · Tetracycline
    Synonyms: Spotted fever due to Rickettsia rickettsii, Spotted fever due to Rickttsia rickettsii