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Cyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approved[A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Products: SANDIMMUN NEORAL CAPSULAS DE 10 MG, INHIBLOCK CICLOSPORINA CAPSULAS DE GELATINA BLANDA 25 MGRufinamide
go.drugbank.com/drugs/DB06201ApprovedClinical trials suggest its efficacy in the treatment of partial seizures. … Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy.
Products: Inovelon 200 mg film-coated tablets, INOVELON FILM-COATED TABLET 200 MGAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalThe pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback mechanism regulates the final activation step of vitamin D in the kidneys. … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].
Categories: Vitamin D and AnaloguesSynonyms: 1α-hydroxyvitamin D3, 1α-hydroxy-vitamin D3Levosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.
Categories: Compounds used in a research, industrial, or household settingProducts: LEVOSIMENDAN EG, Levosimendan Carinopharm 12,5 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Mixtures: M A L D I M, MOMENTUM TABLETASProducts: Riopan Chewable Tablets 480mg, ASIPODAN ÇIĞNEME TABLETI, 60 ADETPotassium bicarbonate
go.drugbank.com/drugs/DB11098ApprovedInvestigationalIt is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. … [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for OTC antacids.[L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.
Mixtures: POT-K 1,56 G EFERVESAN TABLET, 60 ADET, POT-K 1,56 G EFERVESAN TABLET, 15 ADETProducts: Klor-con/ef, KLOR-Con/EFMifepristone
go.drugbank.com/drugs/DB00834ApprovedInvestigationalCurrently under investigation for use in psychotic depression (phase 3 trials). … As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome.
Products: MIFEGYNE TABLETS 200MGDronedarone
go.drugbank.com/drugs/DB04855ApprovedInvestigational[A34604,T28] Additionally, the methyl sulfonyl group in its structure renders dronedarone to be more lipophilic with a shorter half-life than amiodarone. … [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009.
Synonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamideProducts: MULTAQ 400 MG FILM-COATED TABLETS, Film-coated Tablet 400mgBromelains
go.drugbank.com/drugs/DB13281ApprovedInvestigationalBromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase, and several proteas...
Mixtures: Alka-pan Tablets, Chewable Enzymes TabletsProducts: Bromelain 500mg Tablets, Bromelain Tablet 500mgLisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigationalLisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine. … [A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first approved by the FDA in April 2008.[A2230] It was also approved by Health Canada in February 2009.
Products: Apo-lisdexamfetamine Chewable Tablets, Taro-lisdexamfetamine Chewable Tablets