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Spinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. … Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults
Mixtures: Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 9.1-18kg, Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 18.1-27kgCategories: Compounds used in a research, industrial, or household settingUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationaldebated due to ethical concerns related to abortion (Rosato et al, 2016). … A recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily
Categories: Hormonal Contraceptives for Systemic UseCobamamide
go.drugbank.com/drugs/DB11191ApprovedNutraceuticalThis drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids. … It is therefore important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin or cobalamin [L2054].
Mixtures: EnLyte Extra-LN, EnlCategories: Heterocyclic Compounds with 4 or More RingsPrussian blue
go.drugbank.com/drugs/DB06783ApprovedIt is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble form, and an insoluble form. … It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure.
Categories: Compounds used in a research, industrial, or household settingHypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalHypromellose, or hydroxypropyl methylcellulose (HPMC) [L1812], is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. … It is a commonly used as a delivery component in oral pharmaceutical products that provides the release of a drug in a controlled fashion, effectively increasing the duration of release of a drug to prolong
Mixtures: Rohto All-In-One, Visine for Dry Eye True TearsCategories: Compounds used in a research, industrial, or household settingBenzoic acid
go.drugbank.com/drugs/DB03793ApprovedInvestigationalAs the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. … A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
Mixtures: POLY-N OINTMENT, CLISMA LAXCategories: Compounds used in a research, industrial, or household setting, Tests for Gastric SecretionCalcium levulinate
go.drugbank.com/drugs/DB13800ApprovedThe relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide [L2765]. … The resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in calcium lactate
Mixtures: CALCIO AL 10% AMPOLLASLutetium Lu-177 vipivotide tetraxetan
go.drugbank.com/drugs/DB16778ApprovedInvestigational[L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended lutetium Lu-177 vipivotide tetraxetan be granted marketing authorization for the treatment of prostate … [L41280] Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment for prostate-specific membrane antigen–positive metastatic castration-resistant prostate
Categories: Compounds used in a research, industrial, or household settingSynonyms: Lu-177-PSMA-617, lutetium Lu 177-PSMA-617Paritaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationaltherapy option when used in combination with other antivirals for genotypes 1a, 1b, and 4[L852]. … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Paritaprevir as a first line
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsSynonyms: [1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxamide, (2R,6S,12Z,13aR,14aR,16aS)-N-(cyclopropanesulfonyl)-6-[(5-methylpyrazine-2-carbonyl)amino]-5,16-dioxo-2-[(phenanthridin-6-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrroloAminolevulinic acid
go.drugbank.com/drugs/DB00855ApprovedInvestigationalA compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Categories: Photosensitizing Agents for Phototherapy, Sensitizers Used in Photodynamic/radiation TherapySynonyms: 5-ALA, δ-ALA