Search

Displaying results 981 - 990 of 10000 in total
  1. Drug

    Carbimazole

    go.drugbank.com/drugs/DB00389
    Approved

    An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
  2. Drug

    Terazosin

    go.drugbank.com/drugs/DB01162
    ApprovedInvestigational

    Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label][A176831]. … Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate[A176837].

    Mixtures: Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg, Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mgCategories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor Antagonists
  3. Drug

    Sotalol

    go.drugbank.com/drugs/DB00489
    ApprovedInvestigational

    Sotalol is a methanesulfonanilide developed in 1960.[A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992. … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide, β-cardone
  4. Drug

    Seclidemstat

    go.drugbank.com/drugs/DB17117
    Investigational

    Synonyms: N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]- 3-(4-methylpiperazine-1-sulfonyl)benzohydrazide, Benzoic acid, 3-((4-methyl-1-piperazinyl)sulfonyl)-, (2e)-2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazideCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole

    go.drugbank.com/drugs/DB08724
    Experimental

    5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring. This medication is known to target genome polyprotein.

    Synonyms: 5-(5-(4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)pentyl)-3-methyl isoxazole
  6. Drug

    Promazine

    go.drugbank.com/drugs/DB00420
    ApprovedVet approvedWithdrawn

    A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. … It is currently not approved for use in the United States.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsSynonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, N-Dimethylamino-1-methylethyl thiodiphenylamine
  7. Drug

    Gunagratinib

    go.drugbank.com/drugs/DB18191
    Experimental

    Synonyms: 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl)-, (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Chlordiazepoxide

    go.drugbank.com/drugs/DB00475
    ApprovedIllicit

    An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

    Mixtures: Limbitrol DS, LIBKOL FILM TABLET, 50 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  9. Drug

    2'-fluoro-5-ethylarabinosyluracil

    go.drugbank.com/drugs/DB13030
    Investigational

    2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
  10. Drug

    Menthyl salicylate

    go.drugbank.com/drugs/DB11201
    Approved

    Menthyl salicylate is an ester of menthol and salicylic acid [L2808]. This product is used to treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains) [L2810].

    Mixtures: Dr. Ds Super 7 Pain ReliefSynonyms: 1-Menthyl salicylate