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Matrix-M
go.drugbank.com/drugs/DB16369InvestigationalMatrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. … [L27981] This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.
Synonyms: Matrix M, Matrix-MJHU-75528 C-11
go.drugbank.com/drugs/DB14902InvestigationalJHU-75528 C-11 is under investigation in clinical trial NCT03204305 (Brain Imaging of Cannabinoid Receptors).
Methfuroxam
go.drugbank.com/drugs/DB16231InvestigationalMethfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma).
Sasanlimab
go.drugbank.com/drugs/DB18849InvestigationalSasanlimab is under investigation in clinical trial NCT06218069 (Immuno-pet Imaging Responses Administered Immune Checkpoint Inhibitor).
Synonyms: Anti-pd-1 checkpoint inhibitor pf-06801591Apararenone
go.drugbank.com/drugs/DB15024InvestigationalApararenone is under investigation in clinical trial NCT02531568 (Drug Interaction Study of Warfarin and MT-3995).
Categories: Heterocyclic Compounds, 1-RingPsicose
go.drugbank.com/drugs/DB15087ExperimentalPsicose is under investigation in clinical trial NCT02459834 (The Fructose and Allulose Catalytic Effects (FACE) Trial).
GLPG-0259
go.drugbank.com/drugs/DB15190InvestigationalGLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Methylthioinosine
go.drugbank.com/drugs/DB02896ExperimentalAn analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 6-S-methyl-6-thioinosine, 6-methyl-9-ribofuranosylpurine-6-thiolClopamide
go.drugbank.com/drugs/DB13792InvestigationalClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
Categories: Heterocyclic Compounds, 1-RingNDX-3315
go.drugbank.com/drugs/DB18671InvestigationalNDX-3315 is an investigational radiopharmaceutical agent for the diagnosis, treatment monitoring, and management of eosinophilic esophagitis. It is a technetium-99m radiolabeled [heparin].