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Gemigliptin
go.drugbank.com/drugs/DB12412InvestigationalGemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.
Fasiglifam
go.drugbank.com/drugs/DB12491InvestigationalFasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2.
Gandotinib
go.drugbank.com/drugs/DB13040InvestigationalGandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Synonyms: Adenosine triphosphate type 1 competitive inhibitor of JAK2 V617F tyrosine kinaseAZD-1480
go.drugbank.com/drugs/DB12588InvestigationalAZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential Thrombocythaemia Myelofibrosis.
Zelavespib
go.drugbank.com/drugs/DB12638InvestigationalZelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Nolatrexed
go.drugbank.com/drugs/DB12912ExperimentalNolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
ARX517
go.drugbank.com/drugs/DB23076InvestigationalARX517 is under investigation in clinical trial NCT04662580 (ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer).
Pevonedistat
go.drugbank.com/drugs/DB11759InvestigationalPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Itacitinib
go.drugbank.com/drugs/DB12154InvestigationalItacitinib has been used in trials studying the treatment of Melanoma, Carcinoma, Metastatic Cancer, Endometrial Cancer, and B-cell Malignancies, among others.
Tolinapant
go.drugbank.com/drugs/DB16160InvestigationalASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).