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Displaying results 9911 - 9920 of 10000 in total
  1. Drug

    Zelquistinel

    go.drugbank.com/drugs/DB19336
    Investigational

    Zelquistinel is under investigation in clinical trial NCT06547489 (GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder).

  2. Drug

    GC-376 free acid

    go.drugbank.com/drugs/DB15796
    Experimental

    GC-376 is a 3C-like protease (3CL<sup>pro</sup> or M<sup>pro</sup>) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink M<sup>pro</sup> coronavirus[A219026,A219031,A219036,A219041].

  3. Drug

    AVXS-301

    go.drugbank.com/drugs/DB17943
    Experimental

    It is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).[L47077] … AVXS-301 consists of an adeno-associated virus serotype 9 (AAV9) designed to express the superoxide dismutase 1 (SOD1) gene.

  4. Drug

    Zaltoprofen

    go.drugbank.com/drugs/DB06737
    Investigational

    A non-steroidal anti-inflammatory drug approved for use in Japan in 1993.

  5. Drug

    BBM-H901

    go.drugbank.com/drugs/DB17704
    Investigational

    BBM-H901 is a liver-tropic adeno-associated viral (AAV) vector carrying cassette coding hyperactive Padua factor IX (FIX) protein. It is being investigated for the treatment of hemophilia B.[A259048]

  6. Drug

    MVR-C5252

    go.drugbank.com/drugs/DB30379
    Investigational

    MVR-C5252 is a biologic drug. MVR-C5252 is under investigation in clinical trial NCT06126744 (Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252).

  7. Drug

    SARS-CoV-2 Sclamp

    go.drugbank.com/drugs/DB15849
    Investigational

    As of July 13, 2020, the candidate is being tested for safety and immunogenicity in Phase 1 clinical trials in Queensland (ACTRN12620000674932). … The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in combination with a well-established

  8. Drug

    CHO Cells Recombinant Vaccine

    go.drugbank.com/drugs/DB15893
    Experimental

    This vaccine candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and secreted by Chinese Hamster Ovary (CHO) cells[A219758]. … The vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability.

  9. Drug

    PF-04457845

    go.drugbank.com/drugs/DB12012
    Investigational

    PF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence.

  10. Drug

    Coblopasvir

    go.drugbank.com/drugs/DB15315
    Investigational

    Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).