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Displaying results 9931 - 9940 of 10000 in total

Drug
Orgotein
go.drugbank.com/drugs/DB11444
ExperimentalVet approved
Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. … The antioxidant mechanism of SOD is common to most organisms exposed to oxygen. A notable exception is Lactobacillus plantarum.
Drug
Malonyl-CoA
go.drugbank.com/drugs/DB04524
Experimental
A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
Drug
Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
go.drugbank.com/drugs/DB01774
Experimental
Serves as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]
Drug
Aminooxyacetic acid
go.drugbank.com/drugs/DB02079
Experimental
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Drug
Bufotenine
go.drugbank.com/drugs/DB01445
ExperimentalIllicit
A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. … Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.
Categories: N,N-DimethyltryptamineSynonyms: N,N-dimethylserotonin, 5-hydroxy-N,N-dimethyltryptamine
Drug
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
go.drugbank.com/drugs/DB03456
Experimental
These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K. … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives.
Drug
Rocatinlimab
go.drugbank.com/drugs/DB18809
Investigational
In clinical trials, it has shown significant efficacy and safety compared to a placebo. … The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis.
Drug
GC-376 free acid
go.drugbank.com/drugs/DB15796
Experimental
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells … In addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink Mpro coronavirus[A219026,A219031,A219036,A219041].
Drug
Florzolotau F-18
go.drugbank.com/drugs/DB16297
Investigational
PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).
Drug
CHO Cells Recombinant Vaccine
go.drugbank.com/drugs/DB15893
Experimental
This vaccine candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and secreted by Chinese Hamster Ovary (CHO) cells[A219758]. … The vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability.