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Displaying results 9951 - 9960 of 10000 in total
  1. Drug

    GSK-945237

    go.drugbank.com/drugs/DB15345
    Investigational

    GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose

  2. Drug

    Aptazapine

    go.drugbank.com/drugs/DB09305
    Experimental

    Although Aptazapine reached clinical trials, it was never marketed. … Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity.

  3. Drug

    Lysergic acid diethylamide

    go.drugbank.com/drugs/DB04829
    IllicitInvestigational

    Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. … Many emotionally intense experiences can lead to flashbacks when a person is reminded acutely of the original experience.

  4. Drug

    Radotermin

    go.drugbank.com/drugs/DB19127
    Investigational

    Radotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the

  5. Drug

    Cenplacel-L

    go.drugbank.com/drugs/DB19188
    Investigational

    Cenplacel-L is under investigation in clinical trial (Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke) for the treatment of patients

    Synonyms: Cenplacel-L, CENPLACEL-L COMPONENT OF PDA-001
  6. Drug

    1D-myo-inositol 1,4,5-trisphosphate

    go.drugbank.com/drugs/DB03401
    Experimental

    Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. … Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane.

  7. Drug

    2'-fluoro-5-ethylarabinosyluracil

    go.drugbank.com/drugs/DB13030
    Investigational

    2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma

  8. Drug

    Antipain

    go.drugbank.com/drugs/DB15251
    Experimental

    [A214484, A214487] Antipain was used in 2010 to obtain a crystal structure of the _Leishmania major_ oligopeptidase B (OPB), a serine protease that serves as a virulence factor in trypanosomatids. … Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes.

  9. Drug

    Dendritic cells vaccine

    go.drugbank.com/drugs/DB15803
    Investigational

    As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia.

  10. Drug

    AC3056

    go.drugbank.com/drugs/DB05230
    Experimental

    It as since been acquired by Amylin Pharmaceuticals and has completed phase I trials. … AC3056 is a non-peptide antioxidant that acts as an inhibitor of vascular cell adhesion molecule expression originally developed by Aventis Pharmaceuticals.