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Cyclacillin
go.drugbank.com/drugs/DB01000ApprovedA cyclohexylamido analog of penicillanic acid.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(1-aminocyclohexanecarboxamido)penicillanic acidGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-oneBalsalazide
go.drugbank.com/drugs/DB01014ApprovedThe chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. … Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA.
Categories: Non COX-2 selective NSAIDSSynonyms: (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acid, (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acidMinocycline
go.drugbank.com/drugs/DB01017ApprovedInvestigational[A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.
Synonyms: 7-Dimethylamino-6-demethyl-6-deoxytetracycline, (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamideProducts: PERIOCLINE PERIODONTAL OINTMENT 2% W/W, XELTETRA-MTopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalIt works by inhibiting DNA topoisomerases, type I.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinProcainamide
go.drugbank.com/drugs/DB01035ApprovedA derivative of procaine with less CNS action.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamideBenzylpenicillin
go.drugbank.com/drugs/DB01053ApprovedInvestigationalVet approvedAminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans*, and *Enterococcus faecalis*. … Natural penicillins are considered the drugs of choice for several infections caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C and G streptococci
Mixtures: Bicillin C-R 900/300, Bicillin A-P Injection PwsCategories: Penicillin G, Heterocyclic Compounds, 1-RingTocainide
go.drugbank.com/drugs/DB01056ApprovedWithdrawnAn antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
Categories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesSynonyms: 2-Amino-2',6'-propionoxylidide, 2-amino-N-(2,6-dimethylphenyl)propanamideAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Mixtures: SUMIVULIN ® 1.2 G (1 G / 0.2 G), IPICLAV® 1 GCategories: Penicillin G, Heterocyclic Compounds, 1-RingMequitazine
go.drugbank.com/drugs/DB01071InvestigationalMequitazine is a histamine H1 antagonist (antihistamine). … It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors