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Displaying results 9961 - 9970 of 10000 in total
  1. Drug

    Malonyl-CoA

    go.drugbank.com/drugs/DB04524
    Experimental

    A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.

  2. Drug

    N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide

    go.drugbank.com/drugs/DB03456
    Experimental

    These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K. … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives.

  3. Drug

    TPMPA

    go.drugbank.com/drugs/DB16754
    Experimental

    [A245303] GABA<sub>C</sub> receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut … [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313]

  4. Drug

    Rocatinlimab

    go.drugbank.com/drugs/DB18809
    Investigational

    In clinical trials, it has shown significant efficacy and safety compared to a placebo. … The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis.

  5. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. … Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.

    Categories: N,N-DimethyltryptamineSynonyms: N,N-dimethylserotonin, 5-hydroxy-N,N-dimethyltryptamine
  6. Drug

    Florzolotau F-18

    go.drugbank.com/drugs/DB16297
    Investigational

    PMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).

  7. Drug

    Probiorinse

    go.drugbank.com/drugs/DB15870
    Experimental

    [L16368] This strain of bacteria is said to have salubrious effects on the microbiome of the nasal cavity and sinuses.[A220193] … Probiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.

  8. Drug

    Hopantenic acid

    go.drugbank.com/drugs/DB14044
    Experimental

    Hopantenic acid has a unique spectrum of pharmacological effects (nootropic, anticonvulsant, mild activating) in the absence of addiction, hyperstimulation or withdrawal syndrome. [A33115] … Hopantenic acid (Pantogam) is a central nervous system depressant.

    Synonyms: N-pantoyl-GABA
  9. Drug

    BBM-H803

    go.drugbank.com/drugs/DB17700
    Investigational

    It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene. … BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed.

  10. Drug

    Anti-SARS-CoV-2 equine immunoglobulin fragments

    go.drugbank.com/drugs/DB16368
    Investigational

    Anti-SARS-CoV-2 equine immunoglobulin fragments, also known as INOSARS, is a polyvalent passive immunization being tested in the clinical trial NCT04514302 (Safety and Efficacy of Anti-SARS-CoV-2 Equine … [L27796] INOSARS is composed of F(ab’)2 fragments extracted from hyperimmune equine serum.